Vertex Raises 2026 Forecast on $3.44 Billion Quarter as Crinetics Costs Cut Profit 40%
Vertex’s Q3 revenue rose 12% to $3.44 billion as Alyftrek sales nearly tripled, and it raised its 2026 forecast. Crinetics deal costs cut GAAP profit 40%.
World News, Politics and War, Reported from Boston
Boston and Massachusetts business news: companies, deals, layoffs, startups, real estate and jobs.
Vertex’s Q3 revenue rose 12% to $3.44 billion as Alyftrek sales nearly tripled, and it raised its 2026 forecast. Crinetics deal costs cut GAAP profit 40%.
Mass General Brigham layoffs continue as CEO Anne Klibanski warns 85,000 staff of difficult changes; MGB aims to lift operating income from $59M to about $300M.
Seaport Therapeutics ended Q3 with $403.8 million in cash, up 73% since December, and says it is funded into 2029. Its net loss widened 17% to $26.4 million.
Massachusetts business confidence fell 1.0 point to 47.6 in October, AIM said, a third straight month below 50. Only the hiring gauge improved.
Weil Gotshal Boston office: the dissolving law firm opened 37,379 sq. ft. at Lyrik Back Bay in June. Here’s what its wind-down means for the sublease market.
Massachusetts heating oil prices averaged $6.23 a gallon in the latest state survey, up 73% from a year ago, as aid applications jump and Congress stalls.
Brigham nurses strike notice: more than 4,000 nurses plan an open-ended walkout at 7 a.m. Nov. 12 unless a deal is reached at talks resuming Nov. 9.
Amazon withdrew its Westborough drone delivery plan on Oct. 30 after a 510-13 town vote, state hurdles and opposition from 15 nearby communities.
The Toast FTC lawsuit, filed Oct. 29 with 7 states, accuses the Boston restaurant software firm of hidden fees and hard cancellations. Toast says it will fight.
The Bambusa Therapeutics IPO raised $168.9M at $16 a share, then BBTX closed day one at $14.99. Deal terms, where the money goes and our take.